Extracorporeal gas exchange: when to start and how to end?

Toilet training children: when to start and how to train.

Prostate cancer screening—when to start and how to screen?

Prostate-specific antigen (PSA) screening reduces prostate cancer (PCa) mortality; however such screening may lead to harm in terms of overdiagnosis and overtreatment. Therefore, upfront shared decision making involving a discussion about pros and cons between a physician and a patient is crucial. Total PSA remains the most commonly used screening tool and is a strong predictor of future life-t...

how to start interventional radiology

interventional techniques aim to find safer and better ways to treat vascular diseases even in many instances, the interventional radiology solutions has been considered the only treatment option for the patients. interventional radiologists are specialists who perform minimally invasive procedures instead of surgery or other treatments. these procedures apply various imaging and catheterizatio...

when to start dialysis in elderly patients

How to reply to referees' comments when submitting manuscripts for publication

Background: The publication of articles in peer-reviewed scientific journals is a fairly complex and stepwise process that involves responding to referees’ comments. Little guidance is available in the biomedical literature on how to deal with such comments. Objective: The objective of this article is to provide guidance to notice writers on dealing with peer review comments in a way that maxim...